See this discussion on GitHub for some context.
In particular see this comment for some technical details about the SNPlocs packages for dbSNP156.
IMPORTANT: The SNPlocs packages for dbSNP156 both require BioC >= 3.20!
SNPlocs.Hsapiens.dbSNP156.GRCh38_0.99.24.tar.gz is 6.7G and contains 989,474,892 rs ids.
Install it with:
library(BiocManager) repos <- c("http://149.165.171.124/SNPlocs/", BiocManager::repositories()) install.packages("SNPlocs.Hsapiens.dbSNP156.GRCh38", repos=repos)This will take several minutes so make sure to set R_DEFAULT_INTERNET_TIMEOUT to 600 (10 minutes) or more in your .Renviron file:
R_DEFAULT_INTERNET_TIMEOUT=600You will typically need to restart R after making this change.
SNPlocs.Hsapiens.dbSNP156.GRCh37_0.99.24.tar.gz is 6.6G and contains 967,680,084 rs ids.
Install it with:
library(BiocManager) repos <- c("http://149.165.171.124/SNPlocs/", BiocManager::repositories()) install.packages("SNPlocs.Hsapiens.dbSNP156.GRCh37", repos=repos)This will take several minutes so make sure to set R_DEFAULT_INTERNET_TIMEOUT to 600 (10 minutes) or more in your .Renviron file:
R_DEFAULT_INTERNET_TIMEOUT=600You will typically need to restart R after making this change.
Please report problems or ask questions here.