Package: vmrseq
Type: Package
Title: Probabilistic Modeling of Single-cell Methylation Heterogeneity
Version: 1.3.0
Authors@R: person("Ning", "Shen", email = "ning.shen.wk@gmail.com",role = c("aut", "cre"))
Description: High-throughput single-cell measurements of DNA methylation allows studying inter-cellular epigenetic heterogeneity, but this task faces the challenges of sparsity and noise. We present vmrseq, a statistical method that overcomes these challenges and identifies variably methylated regions accurately and robustly.
License: MIT + file LICENSE
Encoding: UTF-8
RoxygenNote: 7.2.3
biocViews: Software, ImmunoOncology, DNAMethylation, Epigenetics, SingleCell,
  Sequencing, WholeGenome
Depends: 
    R (>= 4.5.0)
Imports: 
    bumphunter,
    dplyr,
    BiocParallel,
    DelayedArray,
    GenomicRanges,
    ggplot2,
    methods,
    tidyr,
    locfit,
    gamlss.dist,
    recommenderlab,
    HDF5Array,
    data.table,
    SummarizedExperiment,
    IRanges,
    S4Vectors,
    devtools
Suggests: 
    knitr,
    rmarkdown,
    testthat (>= 3.0.0)
Config/testthat/edition: 3
VignetteBuilder: knitr
URL: https://github.com/nshen7/vmrseq
BugReports: https://github.com/nshen7/vmrseq/issues
git_url: https://git.bioconductor.org/packages/vmrseq
git_branch: devel
git_last_commit: ad3b777
git_last_commit_date: 2025-10-29
Repository: Bioconductor 3.23
