Package: spillR
Type: Package
Title: Spillover Compensation in Mass Cytometry Data
Version: 1.7.0
Authors@R: c(
    person("Marco", "Guazzini",
    email= "m.guazzini@student.maastrichtuniversity.nl", 
    role = c("aut", "cre"), comment = c(ORCID = "0009-0007-8111-5772")), 
    person("Alexander G.", "Reisach" , 
    email = "alexander.reisach@u-paris.fr", 
    role = "aut", comment = c(ORCID = "0009-0003-5057-6278")),
    person("Sebastian", "Weichwald",
    email = "sweichwald@math.ku.dk", 
    role = "aut", comment = c(ORCID = "0000-0003-0169-7244")), 
    person("Christof", "Seiler", 
    email = "christof.seiler@maastrichtuniversity.nl", 
    role = "aut", comment = c(ORCID = "0000-0001-8802-3642")))
Description: Channel interference in mass cytometry can cause spillover 
    and may result in miscounting of protein markers. We develop a 
    nonparametric finite mixture model and use the mixture components 
    to estimate the probability of spillover. We implement our method 
    using expectation-maximization to fit the mixture model.
biocViews: 
    FlowCytometry, 
    ImmunoOncology, 
    MassSpectrometry, 
    Preprocessing, 
    SingleCell, 
    Software, 
    StatisticalMethod, 
    Visualization, 
    Regression  
License: LGPL-3
Encoding: UTF-8
LazyData: false
Config/testthat/edition: 3
RoxygenNote: 7.3.1
Imports: 
    dplyr, 
    tibble, 
    tidyselect,
    stats, 
    ggplot2,
    tidyr,
    spatstat.univar,
    S4Vectors,
    parallel
Depends:
    R (>= 4.3.0),
    SummarizedExperiment,
    CATALYST
Suggests: 
    knitr,
    rmarkdown,
    cowplot,
    testthat (>= 3.0.0),
    BiocStyle,
    hexbin
VignetteBuilder: knitr
git_url: https://git.bioconductor.org/packages/spillR
git_branch: devel
git_last_commit: c3abfa4
git_last_commit_date: 2025-10-29
Repository: Bioconductor 3.23
