Package: TOP
Title: TOP Constructs Transferable Model Across Gene Expression Platforms
Version: 1.11.0
Date: 2022-11-09
Authors@R: 
    c(
        person(
            given="Harry", family="Robertson",
            email = "harry.robertson@sydney.edu.au", role = c("aut", "cre"),
            comment = c(ORCID = "0000-0001-9203-3894")
        ),
        person(
            given="Nicholas", family= "Robertson",
            email = "nicholas.robertson@sydney.edu.au", role = c("aut")
        )
    )
Description: TOP constructs a transferable model across gene expression platforms for prospective experiments. Such a transferable model can be trained to make predictions on independent validation data with an accuracy that is similar to a re-substituted model. The TOP procedure also has the flexibility to be adapted to suit the most common clinical response variables, including linear response, binomial and Cox PH models.
License: GPL-3
URL: https://github.com/Harry25R/TOP
BugReports: https://github.com/Harry25R/TOP/issues
biocViews: Software, Survival, GeneExpression
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3
Imports:
    assertthat,
    caret,
    ClassifyR,
    directPA,
    doParallel,
    dplyr,
    ggnewscale,
    ggplot2,
    ggraph,
    ggrepel,
    ggthemes,
    glmnet,
    Hmisc,
    igraph,
    latex2exp,
    limma,
    magrittr,
    methods,
    plotly,
    pROC,
    purrr,
    reshape2,
    stats,
    stringr,
    survival,
    tibble,
    tidygraph,
    tidyr,
    statmod
Suggests: knitr, rmarkdown, BiocStyle, Biobase, curatedOvarianData, ggbeeswarm, ggsci, survminer, tidyverse
VignetteBuilder: knitr 
LazyData: false
git_url: https://git.bioconductor.org/packages/TOP
git_branch: devel
git_last_commit: 30abd4f
git_last_commit_date: 2025-10-29
Repository: Bioconductor 3.23
