Package: TMixClust
Type: Package
Title: Time Series Clustering of Gene Expression with Gaussian Mixed-Effects Models and Smoothing Splines
Version: 1.33.0
Year: 2017
Date: 2017-06-04
Author: Monica Golumbeanu <golumbeanu.monica@gmail.com>
Maintainer: Monica Golumbeanu <golumbeanu.monica@gmail.com>
Description: Implementation of a clustering method for time series gene expression data based 
             on mixed-effects models with Gaussian variables and non-parametric cubic splines estimation. 
             The method can robustly account for the high levels of noise present in typical gene expression time series datasets.
License: GPL (>=2)
Depends: R (>= 3.4)
biocViews: Software, StatisticalMethod, Clustering, TimeCourse, GeneExpression
Imports: 
    gss,
    mvtnorm,
    stats,
    zoo,
    cluster,
    utils,
    BiocParallel,
    flexclust,
    grDevices,
    graphics,
    Biobase,
    SPEM
Suggests: 
    rmarkdown,
    knitr,
    BiocStyle, 
    testthat
VignetteBuilder: knitr
Encoding: UTF-8
LazyData: true
RoxygenNote: 6.0.1
git_url: https://git.bioconductor.org/packages/TMixClust
git_branch: devel
git_last_commit: d55d2de
git_last_commit_date: 2025-10-29
Repository: Bioconductor 3.23
