Package: SimBu
Title: Simulate Bulk RNA-seq Datasets from Single-Cell Datasets
Version: 1.13.0
Authors@R: 
    person(given = "Alexander",
           family = "Dietrich",
           role = c("aut", "cre"),
           email = "alex.dietrich@tum.de")
Description: SimBu can be used to simulate bulk RNA-seq datasets with known cell type fractions. 
    You can either use your own single-cell study for the simulation or the sfaira database. 
    Different pre-defined simulation scenarios exist, as are options to run custom simulations.
    Additionally, expression values can be adapted by adding an mRNA bias, which produces more
    biologically relevant simulations.
License: GPL-3 + file LICENSE
Encoding: UTF-8
Roxygen: list(markdown = TRUE) 
RoxygenNote: 7.2.3
Imports: 
    basilisk,
    BiocParallel,
    data.table,
    dplyr,
    ggplot2,
    tools,
    Matrix (>= 1.3.3),
    methods,
    phyloseq,
    proxyC,
    RColorBrewer,
    RCurl,
    reticulate,
    sparseMatrixStats,
    SummarizedExperiment,
    tidyr
Suggests:
    curl,
    knitr,
    matrixStats,
    rmarkdown,
    Seurat (>= 5.0.0),
    SeuratObject (>= 5.0.0),
    testthat (>= 3.0.0)
URL: https://github.com/omnideconv/SimBu
BugReports: https://github.com/omnideconv/SimBu/issues
VignetteBuilder: knitr
Config/testthat/edition: 3
StagedInstall: no
biocViews: Software, RNASeq, SingleCell
git_url: https://git.bioconductor.org/packages/SimBu
git_branch: devel
git_last_commit: fc87678
git_last_commit_date: 2025-10-29
Repository: Bioconductor 3.23
